Cytotoxic gold(I)-bearing dendrimers from alkyne precursors.
نویسندگان
چکیده
A series of four dendrimers end-functionalized with gold(I) has been prepared from alkyne-terminated precursors and (tricyclohexylphosphine)gold(I) azide. Isolated yields range from 84-89%, based on gold. The first-generation dendrimer is cytotoxic toward 3T3 mouse fibroblast cells. Apoptosis ensues within 6 h of treatment with gold(I).
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ورودعنوان ژورنال:
- Dalton transactions
دوره 40 32 شماره
صفحات -
تاریخ انتشار 2011